PNA-functional Ligand Conjugates Synthesis
In recent years, the development of PNA into genetic drugs has been one of the research hotspots. However, the biggest obstacle leading to the poor drug ability of PNA is still the problem of cell transport. Covalently linking PNA with a suitable functional ligand with pharmacological activity is a successful attempt in the development of PNA drugs. The successful design of PNA-functional ligand conjugates not only improves the cellular uptake of PNA, but also introduces functional ligand compounds into cells to achieve dual therapeutic effects of PNA and functional ligands. In this conjugate, the ligand not only has the function of assisting the transport, but also exerts its own pharmacological activity.
At Creative Peptides , we always pay attention to the needs of our customers and recognize that careful planning and perfect execution are the key factors for success. Therefore, with our experience and our expertise in the PNA field, for each problem, we will form a professional development team to help you choose the process and technology that meets your research goals.
The following are some synthetic PNA-functional ligand conjugates.
The function of the ligand
|It has pharmacological effects of antipyretic, analgesic, anti-inflammatory, anti-rheumatic, anti-platelet aggregation and improving immunity
|It mainly treats pigs with unknown hyperthermia syndrome and acute hyperthermia inflammation caused by viral infection.
|An aminoglycoside antibiotic that can inhibit bacterial protein synthesis
|Vitamin E is a highly immune drug, which has the functions of scavenging free radicals in the body and anti-aging.
|An alicyclic hydrocarbon whose derivatives can be used as medicines.
Why Choose Us
- We have first-class technology, first-class equipment, years of synthesis experience and a professional test team to provide customers with high-quality PNA services.
- Our trial team is involved in the fields of medicine, pharmacology, and biology, and possesses professional knowledge in many fields, which can better solve the needs of customers.
- We have a strict quality management system, and we are committed to providing reliable testing and cost-effective product analysis services.
The scientists of Creative Peptides are committed to bringing together years of valuable experience to help our customers start the journey of PNA development. For more details, please contact us.
- Liu C.D., et al.Cellular transport of modified peptide nucleic acids. Chinese Journal of Bioengineering. 2016, 32(3): 292-305.
Notice: Products and services are used only for scientific research.